abstract：: ...

journal_title：Clinical and experimental rheumatology

authors： Torreggiani S,Cinnante CM,Torcoletti M,Corona F,Agostoni C,Filocamo G

更新日期：2017-05-01 00:00:00

abstract：:****************************************************************************. ...

journal_title：Clinical and experimental rheumatology

authors： Nagafuchi Y,Shoda H,Sumitomo S,Nakachi S,Kato R,Tsuchida Y,Tsuchiya H,Sakurai K,Hanata N,Tateishi S,Kanda H,Fujio K,Yamamoto K

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVES:We aimed to 1) identify clinical and genetic associations of sacroiliitis (SI) in patients with psoriatic arthritis (PsA), and 2) describe the different radiographic patterns of SI in PsA and their clinical and genetic associations. METHODS:283 PsA patients, fulfilling CASPAR criteria, underwent detailed sk...

journal_title：Clinical and experimental rheumatology

authors： Haroon M,Winchester R,Giles JT,Heffernan E,FitzGerald O

更新日期：2017-03-01 00:00:00

abstract：:Systemic vasculitis is a group of heterogeneous, disabling disorders. Great interest has recently arisen in pathophysiology, clinical phenotypes and therapy of large- and small-vessel vasculitis. The general work hypothesis has been to promote research focused on disease-related pathogenetic pathways, with the ultimat...

journal_title：Clinical and experimental rheumatology

authors： Elefante E,Monti S,Bond M,Lepri G,Quartuccio L,Talarico R,Baldini C

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVES:Eosinophilic granulomatosis with polyangiitis (EGPA) is associated with an inflammation and the presence of antineutrophil cytoplasmic antibodies (ANCA). Thus, we investigated the impact of ANCAs and eosinophilic inflammation on neutrophil activation and extracellular traps (NETs) formation. METHODS:We recr...

journal_title：Clinical and experimental rheumatology

authors： Natorska J,Ząbczyk M,Siudut J,Krawiec P,Mastalerz L,Undas A

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVES:Rheumatoid arthritis (RA) is a chronic, devastating disease. Treat-to-target strategy (T2T) more than the usual care, reduces disease activity by using aggressively all therapeutic options. The aim of the study was to evaluate our hypothesis that T2T strategy using biologic disease-modifying anti-rheumatic d...

journal_title：Clinical and experimental rheumatology

authors： Lampropoulos CE,Orfanos P,Manoussakis MN,Tzioufas AG,Moutsopoulos HM,Vlachoyiannopoulos PG

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVES:The Schnitzler syndrome is a rare inflammatory disorder, with a chronic urticaria-like rash and an IgM (rarely IgG) monoclonal gammopathy as cardinal features. Interleukin-1 β is regarded as the key mediator and the interleukin-1 receptor antagonist anakinra has been proposed as first-line treatment. This ca...

journal_title：Clinical and experimental rheumatology

authors： Vanderschueren S,van der Veen A

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVES:To evaluate the patients' characteristics associated with the clinical decision to request SI-MRI and/or HLA-B27 in patients with SpA in daily practice. METHODS:Patients referred to a rheumatology outpatient-clinic in a national referral-centre were selected. Patients with a clinical diagnosis of SpA accord...

journal_title：Clinical and experimental rheumatology

authors： Bautista-Molano W,Landewé RB,Serna C,Valle-Oñate R,van der Heijde D

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVES:To evaluate the micro-RNA (miRNA) expression profile in patients with early psoriatic arthritis (PsA) in order to assess the role of miRNAs as potential PsA biomarkers. METHODS:The expression of 723 mature miRNAs in peripheral blood mononuclear cells of early PsA patients in comparison with early-rheumatoid...

journal_title：Clinical and experimental rheumatology

authors： Ciancio G,Ferracin M,Saccenti E,Bagnari V,Farina I,Furini F,Galuppi E,Zagatti B,Trotta F,Negrini M,Govoni M

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVES:Rheumatoid arthritis (RA) is characterised by an excess of cardiovascular diseases (CVD) risk, attributable to a synergy between under-diagnosed traditional risk factors (i.e. insulin resistance) and inflammatory disease activity. The aim of the present study was to evaluate the correlation between inflammat...

journal_title：Clinical and experimental rheumatology

authors： Ursini F,D'Angelo S,Russo E,Arturi F,D'Antona L,Bruno C,Naty S,De Sarro G,Olivieri I,Grembiale RD

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVES:Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a serine protease that regulates cholesterol metabolism through low-density lipoprotein receptor degradation and that has been linked with cardiovascular risk. The purpose of the present study was to examine whether PCSK9 levels are related to both abn...

journal_title：Clinical and experimental rheumatology

authors： Ferraz-Amaro I,López-Mejías R,Ubilla B,Genre F,Tejera-Segura B,de Vera-González AM,González-Rivero AF,Olmos JM,Hernández JL,Llorca J,González-Gay MA

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to have an overview of the current approach to psoriatic arthritis (PsA) by a group of Italian rheumatologists. METHODS:Rheumatologists from all around Italy were asked to participate in a survey to give their opinion on a number of statements made by a panel of rheumatologists...

journal_title：Clinical and experimental rheumatology

authors： Marchesoni A,Lubrano E,Manara M,Ramonda R,Salvarani C,Olivieri I

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVES:To assess in daily practice in patients with rheumatoid arthritis (RA) the effect of treatment with first tumour necrosis factor-α inhibitor (TNFi) in quality of life (Qol), disease activity and depict possible baseline predictors for gains in Qol. METHODS:Patients followed prospectively by the Hellenic Reg...

journal_title：Clinical and experimental rheumatology

authors： Boubouchairopoulou N,Flouri I,Drosos AA,Boki K,Settas L,Zisopoulos D,Skopouli FN,Papadopoulos I,Iliopoulos A,Kyriopoulos J,Boumpas DT,Athanasakis K,Sidiropoulos P

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVES:To develop a standardized scoring system to assess the severity of DUs in SSc patients and correlate it with functional outcomes. METHODS:In this cross-sectional, longitudinal study in SSc patients with DUs (n=65) we developed a digital ulcers score (DUS) for the assessment of DUs. DUS and the ABILHAND scor...

journal_title：Clinical and experimental rheumatology

authors： Ahrens HC,Siegert E,Tomsitz D,Mattat K,March C,Worm M,Riemekasten G

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVES:Models for the attribution of neuropsychiatric manifestations to systemic lupus erythematosus (NPSLE) that incorporate timing and type of manifestation, exclusion/confounding or favouring factors have been proposed. We tested their diagnostic performance against expert physician judgment. METHODS:SLE patien...

journal_title：Clinical and experimental rheumatology

authors： Fanouriakis A,Pamfil C,Rednic S,Sidiropoulos P,Bertsias G,Boumpas DT

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVES:To develop recommendations for investigation and monitoring of children with Raynaud's syndrome, based on paediatric evidence collated by a systematic review. METHODS:A systematic review was undertaken to establish the paediatric evidence for assessment and monitoring of Raynaud's syndrome. An expert panel ...

journal_title：Clinical and experimental rheumatology

authors： Pain CE,Constantin T,Toplak N,Moll M,Iking-Konert C,Piotto DP,Aktay Ayaz N,Nemcova D,Hoeger PH,Cutolo M,Smith V,Foeldvari I,Paediatric Rheumatology European Society (PRES) Juvenile Scleroderma Working Group.

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVES:Single nucleotide polymorphisms of CD11a and CD11c have been suggested as susceptibility loci in Korean patients with Behçet's disease (BD). As immunoregulatory roles of CD11c+CD8+T cells were previously observed in multiple autoimmune and autoinflammatory diseases, we aimed to investigate CD11a and CD11c in...

journal_title：Clinical and experimental rheumatology

authors： Park YJ,Park MJ,Park S,Lee ES

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVES:To develop and test a new multidimensional questionnaire for assessment of children with auto-inflammatory disease (AID) such as FMF, PFAPA, HIDS, TRAPS in standard clinical care. METHODS:The juvenile auto-inflammatory disease multidimensional assessment report (JAIMAR) includes 16 parent or patient-centere...

journal_title：Clinical and experimental rheumatology

authors： Konukbay D,Gattorno M,Yildiz D,Frenkel J,Acikel C,Sozeri B,Makay B,Aktay Ayaz N,Barut K,Kisaarslan A,Bilginer Y,Karaman D,Peru H,Simsek D,Aydog O,Unsal E,Gunduz Z,Fidanci BE,Kone-Paut I,Kasapcopur O,Ravelli A,Oz

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVES:The aim of the present study was to compare the clinical results and the quality of life in patients with symptomatic knee osteoarthritis randomised to either a new HA (HYADD 4) or corticosteroid (CS). A separate rationale was to evaluate the safety profile of HYADD 4. METHODS:All the patients presenting fo...

journal_title：Clinical and experimental rheumatology

authors： Bisicchia S,Bernardi G,Tudisco C

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVES:To report the efficacy and tolerability of mycophenolate mofetil (MMF) and azathioprine (AZA) in the management of systemic sclerosis-associated interstitial lung disease (SSc-ILD). METHODS:Patients in the Australian Scleroderma Cohort Study treated with at least 3 months of MMF or AZA for SSc-ILD confirmed...

journal_title：Clinical and experimental rheumatology

authors： Owen C,Ngian GS,Elford K,Moore O,Stevens W,Nikpour M,Rabusa C,Proudman S,Roddy J,Zochling J,Hill C,Sturgess A,Tymms K,Youssef P,Sahhar J

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVES:To compare as proof of concept the sensitivity to change of automated quantification of radiographic wrist and hand joint space width (JSW) with scoring JSW according to the Sharp/van der Heijde scoring method (SHS) in two strategy groups of a treat-to-target and tight-control early rheumatoid arthritis (RA)...

journal_title：Clinical and experimental rheumatology

authors： Huo Y,Veldhuizen RD,van der Heijde DM,Besselink NJ,Jacobs JW,van Laar JM,Viergever MA,Vincken KL,Lafeber FP,de Hair MJ,Society for Rheumatology Research Utrecht investigators.

更新日期：2016-09-01 00:00:00

abstract：:The study of secondary patient data, particularly represented by claims data, has increased in recent years. The strength of this approach involves easy access to data that have been generated for administrative purposes. By contrast, collection of primary data for research is time-consuming and may therefore appear o...

journal_title：Clinical and experimental rheumatology

authors： Richter A,Meißner Y,Strangfeld A,Zink A

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVES:To investigate serum levels of endostatin in a well characterised cohort of patients with primary Sjögren's syndrome (pSS) and healthy controls (HC) and assess associations between these mediators and clinical parameters. METHODS:All patients (n=144) were recruited from the Norwegian systemic connective tis...

journal_title：Clinical and experimental rheumatology

authors： Palm Ø,Ueland T,Garen T,Michelsen AE,Reiseter S,Aukrust P,Aaløkken TM,Molberg Ø

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVES:To describe and evaluate clinical and imaging differences between patients with familial and sporadic early spondyloarthritis (SpA). METHODS:This was a cross-sectional study analysing the baseline dataset from ESPERANZA, a national programme developed for the early identification of patients with SpA. Patie...

journal_title：Clinical and experimental rheumatology

authors： Almodóvar R,Navarro-Compán V,Fernández-Carballido C,Hernández A,De Miguel E,Zarco P,ESPERANZA Study Group.

更新日期：2016-07-01 00:00:00

abstract：:Apart from their pivotal role in dietary lipid absorption and cholesterol homeostasis, bile acids (BAs) are increasingly recognised as important signalling molecules in the regulation of systemic endocrine functions. As such BAs are natural ligands for several nuclear hormone receptors and G-protein-coupled receptors....

journal_title：Clinical and experimental rheumatology

authors： Zhu C,Fuchs CD,Halilbasic E,Trauner M

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVES:To investigate the efficacy and safety of low-dose etanercept treatment after clinical remission of ankylosing spondylitis (AS) in the real world. METHODS:Data on 134 AS patients who were treated with etanercept for more than 12 months and achieved clinical remission (BASDAI<4 and CRP<0.5 mg/dL) were extrac...

journal_title：Clinical and experimental rheumatology

authors： Park JW,Yoon YI,Lee JH,Park JK,Lee EB,Song YW,Lee EY

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVES:Granulomatosis with polyangiitis (GPA) is an autoimmune disease with still unknown etiology. Recent studies indicate that neutrophils extra-cellular traps participate in the pathophysiology of GPA. This study investigates the levels of circulating NET formation markers and neutrophil-platelet interaction in ...

journal_title：Clinical and experimental rheumatology

authors： Surmiak M,Hubalewska-Mazgaj M,Wawrzycka-Adamczyk K,Szczeklik W,Musiał J,Brzozowski T,Sanak M

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVES:To estimate the impact of vaccinations, infections and traumatic life events on the disease activity of a web-based cohort of systemic necrotising vasculitis (SNV) patients. METHODS:Adults diagnosed with SNV self-reported vaccinations, infectious episodes and traumatic life events every 3 months during foll...

journal_title：Clinical and experimental rheumatology

authors： Kernéis S,Turbelin C,Pagnoux C,Launay O,Mahr AD,Guillevin L,Boëlle PY,Hanslik T

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVES:Eosinophilic fasciitis is an uncommon scleroderma-like disorder characterised by induration and thickening of skin and soft tissue, usually associated with peripheral eosinophilia, poorly characterised in childhood. METHODS:We report 3 paediatric cases of eosinophilic fasciitis showing unusual clinical and ...

journal_title：Clinical and experimental rheumatology

authors： Papa R,Nozza P,Granata C,Caorsi R,Gattorno M,Martini A,Picco P

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVES:To determine whether ultrasonographic findings of the synovio-entheseal complex of the hand small joints could be used to differentiate between early rheumatoid and early psoriatic arthritis. METHODS:Thirty-four early rheumatoid and 26 early psoriatic arthritis patients with a prevalent involvement of the h...

journal_title：Clinical and experimental rheumatology

authors： Zabotti A,Salvin S,Quartuccio L,De Vita S

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVES:To assess the sleep quality in primary Sjögren's syndrome (pSS) patients and evaluate its relationship with the disease, quality of life and mood disorders. METHODS:The sleep quality of 29 pSS women and 29 matched controls was assessed by the Pittsburgh Sleep Quality Index (PSQI). Seven domains are grouped ...

journal_title：Clinical and experimental rheumatology

authors： Priori R,Minniti A,Antonazzo B,Fusconi M,Valesini G,Curcio G

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVES:Anti-cyclic citrullinated peptide antibodies (anti-CCP) are a serological marker of rheumatoid arthritis (RA), and also have a prognostic value for more aggressive disease. Whether anti-CCP levels may change during treatment according to clinical response is matter of debate. Likewise, it is unknown whether ...

journal_title：Clinical and experimental rheumatology

authors： Iannone F,Tampoia M,Giannini M,Lopalco G,Cantarini L,Villalta CD,Galeazzi M,Lapadula G

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVES:To date, no biomarker is universally accepted to be a surrogate for active disease being one of major difficulties in follow-up of Takayasu's arteritis (TAK). In this study, we aimed to investigate plasma pentraxin-3 (PTX-3) levels and its correlation with activity in patients with TAK. METHODS:This cross-s...

journal_title：Clinical and experimental rheumatology

authors： Alibaz-Oner F,Aksu K,Yentur SP,Keser G,Saruhan-Direskeneli G,Direskeneli H

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVES:Remitting seronegative symmetrical synovitis with pitting oedema (RS(3)PE) syndrome is a rare inflammatory arthritis, characterised by symmetrical distal synovitis, pitting oedema of the hands and feet, absence of rheumatoid factor, and favourable response to glucocorticoids. The aim of our study is to furth...

journal_title：Clinical and experimental rheumatology

authors： Karmacharya P,Donato AA,Aryal MR,Ghimire S,Pathak R,Shah K,Shrestha P,Poudel D,Wasser T,Subedi A,Giri S,Jalota L,Olivé A

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVES:Understanding health-related quality of life (HRQoL) is important in the management of patients with systemic lupus erythematosus associated pulmonary arterial hypertension (SLE-APAH), however, little is known about HRQoL and its determinants in these patients. METHODS:A total of 60 female SLE-APAH patients...

journal_title：Clinical and experimental rheumatology

authors： Wang H,Guo X,Lai J,Wang Q,Tian Z,Liu Y,Li M,Zhao J,Zeng X,Fang Q

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVES:To describe steroid-sparing in rheumatoid arthritis (RA) patients treated with tocilizumab (TCZ). METHODS:To evaluate the proportion of RA patients treated with more than 5 mg of prednisone (or equivalent)/day and starting TCZ who can receive less than 5 mg/day after 12 months without intensification of dis...

journal_title：Clinical and experimental rheumatology

authors： Saraux A,Rouanet S,Flipo RM,Poncet JC,Fardellone P,Hilliquin P,Idier I,Cantagrel A

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVES:Autoimmune thyroiditis (ATD) has been linked to various forms of arthritis. The relationship with spinal degenerative disc disease (DDD) is not known. We studied the association between ATD and spinal DDD. METHODS:We performed a cross-sectional analysis of patients who had data on both anti-thyroid peroxida...

journal_title：Clinical and experimental rheumatology

authors： Shrestha A,Cohen HW,Tagoe CE

更新日期：2016-03-01 00:00:00

abstract：:Fibromyalgia (FM) syndrome is a chronic disease with unknown aetiology, characterised by widespread pain, fatigue and other functional symptoms. We reviewed the literature of the past year to underline the recent progress in the etiopathogenesis, assessment and therapies of this syndrome, evaluating the articles publi...

journal_title：Clinical and experimental rheumatology

authors： Bazzichi L,Giacomelli C,Consensi A,Atzeni F,Batticciotto A,Di Franco M,Casale R,Sarzi-Puttini P

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVES:To evaluate the efficacy of etoricoxib in patients with axial ankylosing spondyloarthritis (AS) refractory to traditional NSAIDs. METHODS:This was an open label, multicentric, randomised, prospective (4 weeks with and open extension to 6 months), non-controlled study. Consecutive patients with axial AS refr...

journal_title：Clinical and experimental rheumatology

authors： Gratacós J,Moreno Martínez-Losa M,Font P,Montilla C,Fernández-Espartero C,Linares LF,Brito E,Oliva JC,Collantes-Estevez E,Etoricoxib Study Group.

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVES:The effectiveness of anakinra (interleukin-1 receptor antagonist) in early rheumatoid arthritis (RA) is unknown. We evaluated the efficacy of anakinra (combined with methotrexate) in a randomised clinical trial of early active RA patients. METHODS:The Combination Anti-Rheumatic Drugs in Early RA-2 (CARDERA-...

journal_title：Clinical and experimental rheumatology

authors： Scott IC,Ibrahim F,Simpson G,Kowalczyk A,White-Alao B,Hassell A,Plant M,Richards S,Walker D,Scott DL

更新日期：2016-01-01 00:00:00